In the teaser we got to see last October we seen a scene with a train and buffalo, Which seems to be in the Great Plains right out side of black water. When "Americans" first arrived they killed the buffalo to get rid of the native they would often shoot out the window of the train and killing them off. Now back to the story details in red dead redemption they mention that the Pacific union railroad would burn native camps. If the train seen in the trailer came from there pacific union would be a major location for the next installment of the franchise and if we found the date it had opened we could find out the time period of the next game. Side note the train that we see stored away in the building could very well be the one we seen in the trailer. We all also thought it was a ranch that was burning in the trailer but what if it was a native outpost that the railroad company decided to burn down to get rid of the natives in the area ? Maybe that area was known as Beecher hope then after john had left the gang thought it was a good spot to rebuild.